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Using preclinical models of this condition, it was shown that in vitro GLP-1RA liraglutide enhances the nuclear translocation of Nrf2 factor, reducing damage to cells, modulates the MAPK/NF-kB signaling pathway, decreasing the expression of inflammatory factors and proteins, and in vivo protects cognitive dysfunction under conditions of periodic hypoxia in mice

10.1080/19490976.2024.2404141 Gut Microbes 27 GaoP.RinottE.DongD.MeiZ.WangF.LiuY.et al (2024)

Millions of people are living with arthritis, stuck in a cycle of temporary relief and long-term damage

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