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Pharm Res 36:161 Duro-Castano A, Borrs C, Herranz-Prez V, Blanco-Ganda MC, Conejos-Snchez I, Armin A, Mas-Bargues C, Ingls M, Miarro J, Rodrguez-Arias M (2021) Targeting Alzheimers disease with multimodal polypeptide-based nanoconjugates
Cell 35, 427440
This theoretical mechanism could enhance energy expenditure and fat oxidation, though evidence remains mixed
Early human studies demonstrated modest weight loss and appetite suppression, but development was curtailed due to concerns regarding glucagon-mediated hyperglycemia and cardiovascular effects
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