Apply retinoid at night, GHK-Cu serum in the morning or on non-retinoid nights
The amount of scientific evidence that supports the safety and efficacy of non-glutathione skin-whitening treatments is higher than those available for glutathione treatments
Topical cosmetic use: yes, widely available
Glutathione is a powerful antioxidant that can help counteract the oxidative damage and neuroinflammation associated with many neurological disorders like Alzheimer's, Parkinson's, and multiple sclerosis
An RCT in patients receiving cisplatin chemotherapy found that NAC (1,200 mg/day) significantly reduced nephrotoxicity and ototoxicity without reducing antitumor efficacy (Riga et al., Am J Clin Oncol, 2013) [77]
Methylation assay of the SOX2 promoter region The methylation level in the SOX2 promoter region was assessed using a fast bisulfite conversion kit (ab117127, Abcam) according to the manufacturers instructions