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3.1 Tumor initiation/carcinogenic priming ROS may contribute to the early priming stage of carcinogenesis by inducing inflammatory cytokines and DNA damage in normal or non-malignant epithelial cells
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4-Pantetheinylation of formyltetrahydrofolate dehydrogenase (FDH) The figure shows two reactions involving FDH: Panel A: Holo-FDH (the biologically active FDH) catalyzes the conversion of 10-formyltetrahydrofolate into tetrahydrofolate using water and NADP + , releasing CO 2 , NADPH, and a proton (H + )
Arch Physiol Biochem 129(1):6168
