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This is concerning for patients who typically fast overnight before a procedure requiring anesthesia [8]

Thus the glutathione pathway is poised to contribute glutamate without impacting neuronal viability unless there are massive, sustained deficits (16, 23)

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Those in the duloxetine group showed similar improvements in depression and no improvement in anxiety, but DID show reduction in pain

Lancet 1 , 1260 (1977)