PubMed 22962027 TB-4 Phase 1 human safety first-in-human randomized, double-blind, single- and multiple-dose Phase 1 of recombinant human thymosin 4 in healthy volunteers, no serious adverse events: PubMed 34346165
Patients who are pregnant or planning to become pregnant should inform their healthcare provider
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doi: 10.14336/AD.2018.0513 284 TufanE.Gksun SivasG.Grel-GkmenB.Ylmaz-KaraoluS.ErcanD.zbeyliD.et al
The pivotal Phase 2 trial (NCT04881760), published in The New England Journal of Medicine (Jastreboff et al., 2023), enrolled 338 adults with BMI 30 or higher