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Fatty acid oxidation is suppressed through downregulation of PPAR and CPT1, resulting in the accumulation of toxic lipid intermediates like ceramides and acylcarnitines

Despite these challenges, nutritional supplementation remains promising, particularly for patients seeking personalized or alternative therapies

Although the biological activity of CD20 and CD80 are not fully elucidated, CD20 allows specific and effective B-cell depletion and CD80 involves in T cell costimulation (141)

But long-term use of glutathione supplements may lead to zinc deficiency

N-Acetyl-Cysteine (NAC) NAC replenishes glutathione, the brains master antioxidant, and may reduce impulsivity, emotional reactivity, and oxidative stress that worsens focus

It also activates the sympathetic nervous system, which directly stimulates immune cells