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Indeed, particularly under increasingly oxidizing or proliferating growth conditions, during which Trx would be heavily engaged in turning over the peroxiredoxin system ( 45 ) or providing electrons for ribonucleotide reductase ( 46 ), TRP14 is likely to be the major regulator of protein persulfide levels because its activity is not affected by the presence of protein disulfide substrates that are reduced by Trx1 but not by TRP14 ( 22 )

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red coloring of urine (may last 2 to 5 weeks)

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