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Circulating levels of SDF-1 and the expression of receptors for SDF-1 are already increased in patients with heart failure, in the absence of DPP-4 inhibition [72, 73]
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This black box warning is critical to ensure patient safety, particularly in avoiding life-threatening serotonin syndrome in vulnerable populations
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Seven-day-old seedlings of WT, let7-1 , let7-2 , and let7-3 mutants grown on MS plates were treated with 100 nM flg22 for the indicated times
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