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Studies also show it upregulates genes linked to healing and downregulates those associated with damaging inflammation [2]
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PKA can then act on proteins that help control lipolysis
Kwon, D.R., & Park, G.Y
What they found: Mean weight loss: 2.6 kg vs 2.3 kg placebo , a difference of only 0.3 kg (1 %) Statistically non-significant Clinically unsatisfactory for the obesity indication Safety profile remained favorable Why it matters: The study stopped the development of AOD-9604 as a drug
N Engl J Med 2015;372:1832-43
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