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Patients with Leber's hereditary optic neuropathy should avoid cyanocobalamin (hydroxocobalamin is preferred in the UK)

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Hyperdiuresis did need to be discontinued prematurely in two patients (in one case due to a rise in sodium from 120 mM to 128 mM, in another patient due to hypertension)

You can also take a pill every day without any major side effects, unlike an injection that you do not need as often

2- Vary the injection site If you receive vitamin B12 injections often, then its important not to use the same location on the body as your injection site two times in a row

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