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The reduction in CV death with empagliflozin in patients with T2D and PAD translates to a number needed to treat of 29 patients over 3.1 years to prevent one event

But there IS a lot of hype floating around this stack, and most of it comes from people who dont understand the underlying pharmacology or how to properly dose and cycle either compound

The active ingredient in this medication is retatrutide

Rogers, MD, a dermatologist

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In the pancreatic beta cell, that cyclic AMP signal is what links GLP-1 to insulin: it amplifies glucose-stimulated insulin secretion without triggering it on its own, which is why the effect is glucose-dependent and carries little risk of hypoglycemia