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indigestion inflamed stomach (gastritis) the signs include stomach ache, feeling sick (nausea) or being sick (vomiting) reflux or heartburn also called gastro-esophageal reflux disease (GERD) stomach pain bloating of the stomach constipation burping gall stones dizziness tiredness weight loss less appetite gas (flatulence) increase of pancreatic enzymes (such as lipase and amylase)

Participants had no prior history of ischemic heart disease, ischemic stroke, congestive heart failure, or GLP-1RA treatment before surgery

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As a GLP-1, GIP, and glucagon tri-agonist, its being studied for its complex interactions with metabolic signaling pathways making it a compelling subject for researchers exploring weight management, energy regulation, and hormonal response