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In addition, the proportion of participants discontinuing treatment due to AEs was higher in those receiving survodutide than in those receiving placebo or semaglutide (15.9% vs 5.1% vs 4.0%, respectively)

These branded medications are manufactured by specific pharmaceutical companies and have undergone years of clinical trials to receive FDA approval for safety and efficacy

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They also found the semaglutide group had a decreased risk for death from any cause, death from cardiovascular causes, and the measured heart failure composite, which included having an urgent medical visit or hospitalization from heart failure and death from cardiovascular causes

PMID:34053168