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TZP Suppresses Tumor Growth in Diabetic and Non-Diabetic Mouse Models To validate the in vitro findings in vivo, the study employed multiple murine colorectal cancer models, including orthotopic CRC implantation in T1DM mice (induced with streptozotocin, STZ) and subcutaneous CRC models in T2DM mice (induced by high-fat diet plus STZ), as well as normoglycemic controls

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In research, GLP1-S both mimics and amplifies GLP-1s physiological effects, making it highly relevant in studies exploring: Glucose regulation Appetite control and energy balance Obesity and metabolic disorders Appetite Regulation GLP1-S influences appetite control centers in the brain, particularly the hypothalamus, which plays a key role in regulating hunger and satiety[1]

doi: 10.1016/j.clnu.2019.01.020

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Arch Intern Med 1993;153:84958