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1 Recent studies have established a link between BD and IR, with this form of metabolic dysfunction contributing to disease severity, cognitive function, and treatment response
It effectively provides a barrier that selectively limits permeation of luminal toxins and antigens through the mucosa, yet allows absorption of nutrients and water
This tailored approach could allow clinicians to start patients at a personalized initial dose or modify the titration schedule for better tolerance
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10.1038/gt.2016.14 287
There is some evidence suggesting that weight cycling has no effect on the risk of type 2 diabetes [49], and there is no conclusive evidence that previous weight cycling affects body composition or predisposition to obesity
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