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[PMID: 3249813] PubMed record related to this compound for laboratory literature review

This approach preserves sensitivity and reduces total peptide load over time

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GLP-1 RAs have shown potential to protect podocytes by reducing TNF- expression, inhibiting NF-B activation, and preserving mitochondrial function, which collectively support glomerular barrier integrity [70]

In addition, selected safety endpoints will be evaluated using the Safety Analysis Set Orforglipron (SAS-OFG), which included data after the first dose of orforglipron for participants randomized to orforglipron and data after initiation of rescue orforglipron for participants randomized to placebo

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