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Human genetics illuminates the paths to metabolic disease
It is the active pharmaceutical ingredient in Novo Nordisks Ozempic (FDA-approved 2017 for Type 2 diabetes), Wegovy (FDA-approved 2021 for chronic weight management in adults with obesity, and 2024 expanded for cardiovascular risk reduction in adults with overweight/obesity and established cardiovascular disease), and Rybelsus (oral form, Type 2 diabetes)
The active ingredient and inactive components are blended following established non sterile compounding procedures
It reduces systolic blood pressure by 14 mmHg, lowers non-HDL cholesterol by 15-20%, decreases triglycerides by 35-45%, and reduces inflammatory markers like hs-CRP
Each of these brands is prescribed for specific purposes
People who are allergic to peanuts, for example, may also be allergic to tree nuts and shellfish
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