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Mechanism of Action and Pharmacokinetics GLP-1 RAs enhance glucose-dependent insulin secretion, suppress glucagon release, delay gastric emptying, and promote satiety

Boucher J, Kleinridders A, Kahn CR

Combined, these amino acids stop the body from storing excess fat and help boost internal processes to break fat down for removal

This mechanism complements the angiogenic and proliferative effects of the peptide, ensuring that new cells not only form but also reach the locations where they are needed

Face serums and creams: Clinical standard: 1-3% concentration Maximum typically used: 4% concentration Application: Once or twice daily Duration: Minimum 8-12 weeks for visible results Eye area products: Concentration: 1-2% (lower for sensitive periorbital skin) Application: Once daily, typically evening Amount: Pea-sized for both eyes Scalp solutions for hair: Concentration: 0.5% solution common Application: 1-2ml to affected areas once or twice daily Duration: 3-6 months minimum for meaningful changes Higher concentrations do not always mean better results with topicals

The entire process takes less than 30 seconds, and in my experience, a once-weekly injection (Ozempic, Trulicity, and Mounjaro) is preferred by many over a daily pill