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76 And, MTHFD1 depletion reduces both the frequencies of circulating melanoma cells in the blood and metastatic disease burden in mice bearing melanoma, 77 suggesting that NAPDH homeostasis represents therapeutic targets to impede distant metastasis

In addition, molecular docking of one of the tomato GST member, SlGSTU5, and ligand suggested that the activity of SlGSTs could be enhanced by the use of safeners for the purpose of crop improvement and stress defiance ( It has been well documented that GSTs assist in regulating oxidative stress metabolism

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