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PMC 4145307

10.1046/j.1365-2125.2003.01907.x 53 SterneJ.HernnM.ReevesB.SavoviJ.BerkmanN.ViswanathanM.et al (2016)

The AOD-9604 reddit reviews community reports mixed approaches: approximately 60% run continuous 12-week protocols followed by 4-8 week breaks to assess maintenance and avoid receptor desensitization, while 40% use ongoing protocols with periodic dose adjustments based on body composition progress

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David Sinclair, a leading voice in longevity research, has stated: NAD+ is the closest we've gotten to a fountain of youth.[2] His research highlights how NAD+ activates pathways that mimic caloric restriction, a known extender of lifespan in models

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