[33] first documented a reduced incretin effect in patients, with type 2 diabetes
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doi:10.1038/s41591-023-02669-x Nunn E, Jaiswal N, Gavin M, et al
Schedule a consultation if you experience any signs of contraceptive failure while taking tirzepatide, including missed periods (if not expected with your contraceptive method), unusual bleeding patterns, or symptoms of early pregnancy such as breast tenderness, nausea beyond what is expected from tirzepatide, or fatigue