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Fatty acid composition in major depression: decreased omega 3 fractions in cholesteryl esters and increased C20: 4 omega 6/C20:5 omega 3 ratio in cholesteryl esters and phospholipids J Affect Disord 1996

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that somehow we're not getting as much pleasure or not getting as much reward because dopamine is induced by many of these substances that we take, which is part of the pleasure in taking them." Another may have to do with the neurotransmitter GABA

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