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Effects of crocin and saffron aqueous extract on gene expression of SIRT1, AMPK, LOX1, NF-B, and MCP-1 in patients with coronary artery disease: A randomized placebo-controlled clinical trial
Lin et al., 2023
In fact, Hans probe could be potentially used as a peroxynitrite probe, similar to the H 2 O 2 probe Hyper, which is reversibly oxidized by H 2 O 2 and reduced by thioredoxin 35
However, dose-dependent gastrointestinal effects limit efficacy, so drugs with GLP-1 and GCG pharmacology can also target alternative pathways and may expand the therapeutic index (132)
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Because this protocol supports endogenous GH production , many benefits are sustained even after therapy ends
