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Thus, due to the activity of DPP-4 only 1015% of secreted GLP-1 reaches circulation intact
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To further characterize and validate our findings from the primary analysis, additional subgroup comparisons were conducted across three distinct matched cohort analyses: (1) GLP-1 RAs versus insulin monotherapy, (2) GLP-1 RAs versus metformin monotherapy, and (3) GLP-1 RAs versus SGLT2 inhibitor monotherapy
Angela Tran
doi:10.1210/endo.139.7.6092 41
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