The 2024 semaglutide phase 2 RCT and the Weill Cornell cohort data are the most rigorous current evidence showing bone loss - but reasonable endocrinologists interpret even those findings with appropriate uncertainty about generalizability
Kumaran S, Panneerselvam KS, Shila S, Sivarajan K, Panneerselvam C: Age-associated deficit of mitochondrial oxidative phosphorylation in skeletal muscle: role of carnitine and lipoic acid
Neurodegeneration and AD models: exenatide Considering the successful neuroprotection of GLP-1RAs in in vivo diabetic models, researchers have directly tested GLP-1RAs in in vivo models of neurodegenerative diseases, including toxin-induced and transgenic models
A glutathione push is a concentrated dose of pure glutathione delivered via IV syringe in 1015 minutes
Manufacturing readiness for an antibody in a high-prevalence chronic market, as well as payer positioning and trial scalability across community sites, will determine whether a promising safety profile can translate into a viable late-stage program
Patients do not need to memorize the chemistry