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Use extra caution if you have kidney disease, follow a medically restricted protein diet, have food allergies, avoid pork or beef for religious reasons, or take medications that require consistent diet patterns

JAMA Surg 149:275287 (1992) Gastrointestinal surgery for severe obesity: National Institutes of Health Consensus Development Conference Statement March 2527 1991

In the future, there may be expanded indications for use, such as dumping syndrome or chronic diarrhoeal conditions

The pharmacological antagonists of MC4R appeared to lead to weight gain, while the agonist was observed to lead to the contrary in laboratory experiments

[PMID: 532501] PubMed record related to this compound for laboratory literature review