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If left untreated, severe vitamin B12 deficiency can cause irreversible damage to the nervous system

These personalized schedules account for individual response patterns and goals, optimizing the timing of different compounds throughout the year

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Federal Register, 90(15), 1234-1240

it contains a cyanide molecule attached to the core cobalamin ion

D57 (CTR) and D254 (G), were predicted protonated, however, visual inspection did not support this prediction because of their solvent-exposed location and, therefore, were modelled in the anionic side chain form