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L-methylmalonyl-CoA to Succinyl-CoA Conversion: Methylcobalamin is also a coenzyme for the enzyme methylmalonyl-CoA mutase

Strand Bio keeps that comparison limited to catalog information: names, offered vial sizes, molecule classes, categories, catalog price, and access status

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Function Cofactor for methionine synthase Methylcobalamin is required for the function of the folate-dependent enzyme, methionine synthase

Both activate AMPK, but through distinct mechanisms: metformin inhibits complex I of the mitochondrial electron transport chain, raising the cellular AMP:ATP ratio and thereby activating AMPK indirectly