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While data specific to GLP-1 RA discontinuation remain limited, a large-scale prospective study on weight cycling (mean age 63.6 years, at high risk of T2DM) reported that weight regain was typically characterized by an adverse shift in body composition, with FM returning to baseline levels while FFM declined by 1.50 kg (95% CI 0.662.35)

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But it wasnt as simple as collecting vials of reptile saliva to use in a lab