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Injecting close to the affected area is believed by some to provide more localized effects, though systemic distribution occurs regardless of injection site
Anyone with personal cancer history, family history of hormone-sensitive cancers, or current suspicious masses should avoid GH secretagogues and IGF-1 elevating protocols
Moreover, elderly people are also at higher risk as the ability to absorb vitamin B12 naturally declines with age
For general maintenance or mild symptoms, once-daily dosing typically suffices and simplifies the protocol
In a rat model of intervertebral disc degeneration, MOTS-c injection preserved disc height (82.4% versus 58.7% in the untreated group), restored MRI signals indicating improved disc hydration, and reduced histological degeneration scores by 44% compared to untreated controls
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