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genetic associations with other risk factors were obtained from summary statistics in the Neale Lab GWAS of the UK Biobank, controlling for age, age 2 , and 20 principal components (Additional file 1: Table S1)

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Extracorporeal treatment to enhance VPA elimination, preferentially using intermittent hemodialysis, is only recommended in the most severe cases [7, 8]

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XuYJiangWChenGZhuWDingWGeZet alL-carnitine treatment of insulin resistance: a systematic review and meta-analysis