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In previous studies, p53 TAD was shown to significantly influence the DNA selectivity of p53 DBD, with the acidic residues of TAD believed to contribute to this selectivity through interactions with the basic residues of DBD 54

Research protocols typically use concentrations ranging from 0.1-10 mM, depending on the experimental objectives and cell line characteristics

Mol Biol Cell 20:28642873

After reconstitution, store at 28 C , protect from light, and avoid repeated temperature cycling