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The increased oxidant burden derives from the fact that cigarette smoke contains an estimated 10 14 free radicals/puff and that many of these, such as tar semiquinone, which can generate H 2 O 2 by the Fenton reaction, are relatively long-lived (178, 194, 268)

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Vitamin Supplementation Reduces Blood Homocysteine Levels: A Controlled Trial in Patients with Venous Thrombosis and Healthy Volunteers. Arteriosclerosis, Thrombosis, and Vascular Biology, vol

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Follow proper aseptic techniques, such as washing hands thoroughly and disinfecting the injection site with alcohol swabs