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(This is associative evidence and may reflect confounding by indication, surveillance patterns, and glycaemic differences.) For post-marketing pharmacovigilance, FAERS-based analyses of semaglutide identify multiple safety signals (e.g., gastrointestinal obstruction-related terms, dehydration/volume depletion in some GLP-1RA analyses), but vulvovaginal dryness/infection/discharge/pain are not prominent as labelled risks in the major semaglutide FAERS disproportionality paper retrieved here

However, some individuals have reported experiencing hair shedding during use

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Anyone who experiences rapid and significant weight loss whether through bariatric surgery or other means may experience similar body changes. Beyond cosmetic changes, losing glute mass can also impact how your body moves and functions