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This prediction of enhanced receptor engagement provides a structural model for multi-receptor targeting, which can be evaluated in future experimental studies of downstream metabolic pathways
Samples were digested in an oven at 60 C for 1 h
Cellular survival signaling pathway dynamics under defined experimental conditions
10.3892/etm.2018.5799 71
The function of TMAO in causing endoplasmic reticulum (ER) stress and insulin resistance in diabetes is well-documented, with TMAO levels greater in type 2 diabetics
All qRTPCR assays were performed on the QuantStudio 5 Real-Time PCR system (Applied Biosystems, CA, USA) with Power-Up SYBR Master Mix (Applied Biosystems, CA, USA)
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