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Excessive pro-inflammatory cytokines suppress the negative feedback of the HPA axis, boost the permeability of the blood-brain barrier, decrease the synthesis of neurotransmitters such as serotonin (5-HT), and ultimately lead to the onset of depression (Haroon and Miller, 2017

BPC-157 has been studied for gut healing, tendon and ligament repair, and anti-inflammatory effects

Motivation is provided by inflammatory signals from the injury

doi: 10.1016/j.ecoenv.2024.117332 12

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