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pHNaOH/HClThe pharmaceutical formulation may further include one or more pH adjusting reagents, such as NaOH and/or HCl

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Strikingly, addition of 50 M compound 3 , 6 , 9 or 10 for 24 h reduced GST-PFO staining intensity by 2.32.8-fold in U18666A-treated SH-SY5Y cells, respectively

Additional Phase 3 trials are still underway, including TRIUMPH-2 (evaluating retatrutide in adults with obesity and type 2 diabetes) and TRIUMPH-3 (evaluating cardiovascular outcomes), with results expected later in 2026

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