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The obesity drug market continues to mature with US approval for the first generic version of a glucagon-like peptide (GLP)-1 drug thats indicated for weight loss
True fat regain follows a predictable timeline based on discontinuation studies: 15-20% weight regain in months 1-3, another 20-30% in months 4-9, plateauing around 70-80% total regain by 12-18 months
Important caveat: External prescriptions typically aren't covered by Kaiser pharmacyyou'll pay out of pocket
In June 2025, the EMAs safety division, the Pharmacovigilance Risk Assessment Committee (PRAC), concluded a review of GLP-1 medication and its risk of patients developing NAION
One study found that after people took semaglutide for 20 weeks and then stopped, they gained back almost 7% of their body weight within a year
