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GHSR and GLP-1R are expressed in NG neurons and transported within the vagal afferents To determine whether a distinct subset of NG neurons received signals from the gastric corpus, we performed a retrograde tracer study in mice

The upregulated TXNIP downregulates MafA and thus inhibits insulin expression in LOsG-treated -cell

FIGURE 4 Further supporting this mechanism, Western blot confirmed dose-dependent MPC2 protein upregulation in colons of LEO-treated mice (Figure 4C)

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It has a molecular weight of approximately 4,113 daltons