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A novel small molecule, N-(4-(2-pyridyl)(1,3-thiazol-2-yl))-2-(2,4,6-trimethylphenoxy) acetamide, selectively protects against oxidative stress-induced cell death by activating the Nrf2-ARE pathway: therapeutic implications for ALS

GSH depletion in RPE cells increased the number of red puncta, indicating an increase in autophagic flux (Fig

Because intracellular cysteine level is usually below 100 M under the physiological conditions 18,19 , the interference of RT signals from cysteine is minimal

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