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One possible reason is straining during bowel movements, which is especially likely if you have diarrhea or constipation
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For example, studies on semaglutide 2.4 mg daily reveal an average 8% weight loss in individuals with diabetes over 60 weeks, while those without diabetes see closer to 11%
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It should also be noted that during our study period, semaglutide was reported to exhibit both the highest weight-reducing effect [5, 18] and reduction of glycemia [6], which could be a contributory factor to the increase in the use of this substance in particular
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