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Study outcomes The GWAS summary statistics of MASLD were from a genome-wide meta-analysis of 4 cohorts (including eMERGE, UK Biobank, Estonian Biobank, and Finngen study) in European ancestry (case/control: 8434/770180) as a discovery dataset [31], and another GWAS statistic of MASLD comprising 11 leading European tertiary liver centers was chosen as a replication dataset (case/control: 4761/373227) [32]