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Patients with inflammatory bowel disease or other significant gastrointestinal disorders may experience exacerbation of their symptoms with tirzepatide therapy

Vitamin D-VDR (vitamin D receptor) regulates defective autophagy in renal tubular epithelial cell in streptozotocin-induced diabetic mice via the AMPK pathway

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MC4 receptors are considered central to appetite research because receptor dysfunction or genetic deletion consistently produces obesity and hyperphagia phenotypes in animal models

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