Tanner, C
compared the levels of proinflammatory cytokines in tears between GD patients and healthy controls and discovered that the release of IL-1, IL-6, IL-13, IL-17A, IL-18, TNF-, and RANTES significantly increased in patients with GD and Graves ophthalmopathy (GO) (34)
However, systemic administration of lactate oxidase carries the risk of off-target H2O2 toxicity, underscoring the need for tumor-specific delivery systems to improve safety and therapeutic outcomes
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If they inject it into a vein, the body may lose a high proportion as the person passes urine
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