When buying horse gelatin, look for third-party certifications (like NSF or Informed-Sport) and clear labeling of a GMP-compliant facility
Its mechanism of action is based on selective activation of the ghrelin receptor (GHS-R1a), which signals the hypothalamus and anterior pituitary to increase pulsatile GH secretion
They have also been shown to have positive effects on body composition and glucose levels
Probiotic-rich foods like yogurt and kefir can also support overall gut health
You've been doing this for 30 years, and I think one of the probably biggest changes that have happened over the time that you've been working on obesity is that we've come to see obesity as a chronic recurring disease
Patients often exhibit structurally abnormal, swollen mitochondria with disrupted cristae, impaired mitochondrial recycling (a process called mitophagy), and chronically elevated levels of reactive oxygen species