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However, in a subanalysis of participants with low vitamin B 12 status at baseline (n= 101), the B-vitamin supplementation slowed the decline in bone mineral density (total hip and femoral neck but not lumbar spine) (116)
Xu, J., Teran-Garcia, M., Park, J
Science 246 , 382385 (1989)
Dosage and Administration
The C20 fatty diacid moiety enabling albumin binding extends the pharmacokinetic half-life to approximately 6-7 days, making once-weekly research dosing protocols practical
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