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Patients who titrate to 5 mg or 7.5 mg during this window see a second acceleration in loss, typically adding another 3-5% total body weight reduction by week 12
194 All patients benefit from dietary and lifestyle modification: 66 reducing caloric intake to 12001500 or 15001800 calories per day for women and men respectively, 195 with incorporation of moderate-intensity exercise of 150 minutes per week
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PSIC, prolonged severe intrahepatic cholestasis
reassess after several weeks using objective logs and patient-reported feedback
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