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Four, resmetirom confers significant advantages to patient cohorts who do not meet the indication of GLP-1 therapies, including individuals who have already attained weight reduction and populations not afflicted with diabetes
Combining GLP-1 medications and phentermine can enhance appetite control, boost energy levels, and potentially lead to greater weight loss compared to using either medication alone
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However, although TZDs can have cardiac benefits in selected patient cohorts 14 , the development of many Glitazars was terminated due to potential unfavourable effects on the cardiovascular and/or renal system 15