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The Ile-52 backbone amide forms a hydrogen bond with the backbone carbonyl of the GSH cysteinyl group and Glu-64 forms a salt-bridge with the amino group of -glutamyl moiety of GSH

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It was found that the intracellular ROS level of 4T1 and B16 cells also increased significantly after treatment with NSBSO or NS, and more ROS was produced in B16 cells than in 4T1 cells (Additional file 1: Fig

Few explain what those numbers actually mean for the performance of a finished product

Levels of HNMT activity in humans are regulated genetically

Disrupted GSH homeostasis has been linked to pathologies including cancer, neurodegenerative disorders, and immune dysfunction (4446)